Edict of Milan
Constantine and Licinius end the persecution of Christians

Emperors Constantine and Licinius agreed at Mediolanum to grant freedom of worship and restore property seized from Christians. Persecution ended, and with Constantine's patronage Christianity rapidly became the religion of the empire.
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Meanwhile around the world (±25 years)
Africa
- c. 330 Aksum adopts Christianity — 17 years later
Asia
- c. 320 Founding of the Gupta Empire — 7 years later
Alive at the time
- Constantine the Great (aged 41)
- Anthony the Great (aged 62)