Panchronia

Cocoliztli epidemic

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1545–1548 · New Spain (Mexico) · Americas · Nature

A mystery fever wipes out much of Mexico's native population

Cocoliztli epidemic
en:Bernardino de Sahagún (1499-1590), compiler. Original… · Public domain · Wikimedia Commons

A mysterious hemorrhagic fever the Aztecs called cocoliztli killed an estimated 5 to 15 million people, a large share of Mexico's native population. Its cause is still debated; one hypothesis is paratyphoid fever. That same year, the Council of Trent opened in Europe.

State: Spanish Empire, Spanish Empire

Meanwhile around the world (±25 years)

Europe

Eastern Europe & Russia

Middle East

Africa

Asia

Alive at the time