Founding of São Paulo
A Jesuit mission that became South America's largest city

On 25 January 1554 the Jesuits Manuel da Nóbrega and José de Anchieta founded a mission to convert the Indians, the college of São Paulo, on the plateau beyond the coastal mountains. In the 17th century bands of bandeirantes set out from here into the Brazilian interior in search of slaves and gold.
Wikipedia (Russian) · Wikipedia (English) · 16th century
Meanwhile around the world (±25 years)
Europe
- 1543 Copernicus publishes heliocentrism — 11 years earlier
- 1545–1563 Council of Trent — 9 years earlier
- 1555 Peace of Augsburg — 1 year later
- 1565 Great Siege of Malta — 11 years later
- 1568–1648 Dutch Revolt — 14 years later
Eastern Europe & Russia
- 1547 Ivan IV crowned Tsar — 7 years earlier
- 1555–1561 Saint Basil's Cathedral — 1 year later
- 1556 Russia annexes Astrakhan — 2 years later
- 1558–1583 Livonian War — 4 years later
- 1569 Union of Lublin — 15 years later
Africa
- 1529–1543 Ahmad Gragn invades Ethiopia — 25 years earlier
Asia
- 1556 Shaanxi earthquake — 2 years later
- 1556 Akbar and the Second Battle of Panipat — 2 years later
Alive at the time
- Michelangelo (aged 79)
- Ivan the Terrible (aged 24)
- Elizabeth I (aged 21)
- Akbar the Great (aged 12)
- Tokugawa Ieyasu (aged 11)
- Miguel de Cervantes (aged 7)
- Bartolomé de las Casas (aged 70)
- Suleiman the Magnificent (aged 60)
- Charles V (aged 54)
- Hurrem Sultan (Roxelana) (aged 49)