Ottoman–Mamluk War of 1485–1491
Two Muslim powers fight over Cilicia

Bayezid II and Sultan Qaitbay of Egypt fought for six years over Cilicia and the frontier beyliks of Dulkadir and the Ramadanids. The Mamluks won several battles and the peace of 1491 kept the old borders, but 25 years later the Ottomans conquered Egypt.
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Meanwhile around the world (±25 years)
Europe
- 1469 Marriage of Ferdinand and Isabella — 16 years earlier
- 1478 Spanish Inquisition established — 7 years earlier
- 1492 Fall of Granada — 7 years later
- 1494 Treaty of Tordesillas — 9 years later
- 1508–1512 Sistine Chapel ceiling — 23 years later
Eastern Europe & Russia
- c. 1469 Afanasy Nikitin's journey to India — 16 years earlier
- 1478 Annexation of Novgorod by Moscow — 7 years earlier
- 1480 Great Stand on the Ugra River — 5 years earlier
Africa
- 1488 Dias rounds the Cape of Good Hope — 3 years later
Asia
- 1467–1477 Ōnin War — 18 years earlier
- 1498 Vasco da Gama reaches India — 13 years later
- 1510 Portugal takes Goa — 25 years later
Americas
- 1492 Columbus reaches the Americas — 7 years later
- 1497 John Cabot reaches North America — 12 years later
Alive at the time
- Christopher Columbus (aged 34)
- Leonardo da Vinci (aged 33)
- Nicolaus Copernicus (aged 12)
- Michelangelo (aged 10)
- Martin Luther (aged 2)
- Ashikaga Yoshimasa (aged 49)
- Ivan III (aged 45)
- Isabella I of Castile (aged 34)
- Richard III (aged 33)
- Amerigo Vespucci (aged 31)