The Parthians take Mesopotamia
Mithridates I is crowned at Seleucia: Parthia is a great power

In 141 BC the Parthian king Mithridates I captured Babylonia and held a formal investiture at Seleucia on the Tigris. Mesopotamia became the heart of the Parthian empire, leaving the Seleucids with little more than Syria.
Wikipedia (Russian) · Wikipedia (English) · 2nd century BC
Meanwhile around the world (±25 years)
Europe
- 146 BC Rome destroys Corinth — 5 years earlier
- 133 BC Tiberius Gracchus' reform and murder — 8 years later
Africa
- 149 BC–146 BC Third Punic War — 8 years earlier
Asia
- c. 138 BC–126 BC Zhang Qian's mission to the West — 3 years later
Alive at the time
- Emperor Wu of Han (aged 15)
- Sima Qian (aged 4)
- Zhang Qian (aged 23)