Battle of Alcácer Quibir
King Sebastian falls, and Portugal loses its independence

Moroccan forces destroyed the army of King Sebastian I of Portugal, who died in battle along with two Moroccan claimants. Morocco rose under Ahmad al-Mansur, while Portugal passed to the Spanish king in 1580.
Wikipedia (Russian) · Wikipedia (English) · 16th century
Meanwhile around the world (±25 years)
Europe
- 1571 Battle of Lepanto — 7 years earlier
- 1572 St Bartholomew's Day Massacre — 6 years earlier
- 1582 Gregorian calendar — 4 years later
- 1588 Defeat of the Spanish Armada — 10 years later
- 1598 Edict of Nantes — 20 years later
Eastern Europe & Russia
- 1555–1561 Saint Basil's Cathedral — 23 years earlier
- 1569 Union of Lublin — 9 years earlier
- 1582 Yermak's conquest of Sibir — 4 years later
- 1598–1613 Time of Troubles — 20 years later
Asia
- 1556 Shaanxi earthquake — 22 years earlier
- 1556 Akbar and the Second Battle of Panipat — 22 years earlier
- 1592–1598 Imjin War — 14 years later
- 1600 Battle of Sekigahara — 22 years later
Americas
- 1600 Eruption of Huaynaputina — 22 years later
Alive at the time
- Ivan the Terrible (aged 48)
- Elizabeth I (aged 45)
- Akbar the Great (aged 36)
- Tokugawa Ieyasu (aged 35)
- Miguel de Cervantes (aged 31)
- William Shakespeare (aged 14)
- Galileo Galilei (aged 14)
- Philip II of Spain (aged 51)
- Yermak Timofeyevich (aged 46)
- Oda Nobunaga (aged 44)