Jenner's first vaccination
Cowpox shields against smallpox — vaccination is born

In May 1796 country doctor Edward Jenner inoculated young James Phipps with cowpox and showed it protected against smallpox. Vaccination was born — a method that saved hundreds of millions of lives and later made smallpox eradication possible.
Wikipedia (Russian) · Wikipedia (English) · 18th century
Meanwhile around the world (±25 years)
Eastern Europe & Russia
- 1772–1795 Partitions of Poland — 24 years earlier
- 1783 Russian annexation of Crimea (1783) — 13 years earlier
- 1812 Napoleon's invasion of Russia — 16 years later
Africa
- 1798 Battle of the Pyramids — 2 years later
- 1804–1903 Usman dan Fodio's jihad and the Sokoto Caliphate — 8 years later
- 1805–1848 Muhammad Ali becomes ruler of Egypt — 9 years later
Asia
- 1815 Eruption of Mount Tambora — 19 years later
- 1817–1824 First cholera pandemic — 21 years later
- 1819 Raffles founds modern Singapore — 23 years later
Americas
- 1776 US Declaration of Independence — 20 years earlier
- 1787 US Constitution — 9 years earlier
- 1791–1804 Haitian Revolution — 5 years earlier
- 1803 Louisiana Purchase — 7 years later
- 1810–1826 Spanish American wars of independence — 14 years later
Oceania
- 1788 First Fleet arrives in Australia — 8 years earlier
Alive at the time
- Catherine the Great (aged 67)
- George Washington (aged 64)
- Johann Wolfgang von Goethe (aged 47)
- Napoleon Bonaparte (aged 27)
- Ludwig van Beethoven (aged 26)
- Simón Bolívar (aged 13)
- Qianlong Emperor (aged 85)
- Immanuel Kant (aged 72)
- Alexander Suvorov (aged 66)
- James Watt (aged 60)